https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Prevalence and Impact of Cerebral Microbleeds on Clinical and Safety Outcomes in Acute Ischaemic Stroke Patients Receiving Reperfusion Therapy: A Systematic Review and Meta-Analysis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53567 Wed 28 Feb 2024 16:32:39 AEDT ]]> An examination of the neutralization of in vitro toxicity of Chinese cobra (Naja atra) venom by different antivenoms https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38528 Wed 27 Oct 2021 16:09:11 AEDT ]]> Relationship between levels of pre-stroke physical activity and post-stroke serum insulin-like growth factor I https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45071 p = 0.06) or as a significant effect (ΔIGF-I, p = 0.03) after all the adjustments. Specifically, for each unit of PA, ΔIGF-I increased by 9.7 (95% CI 1,1−18.4) ng/mL after full adjustment. This supports the notion that pre-stroke PA is independently related to ΔIGF-I.]]> Wed 26 Oct 2022 12:29:03 AEDT ]]> Phospholipase A2 (PLA(2)) as an Early Indicator of Envenomation in Australian Elapid Snakebites (ASP-27) https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:41985 Tue 16 Aug 2022 15:55:22 AEST ]]> A senescence bystander effect in human lung fibroblasts https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45373 2O₂ or etoposide; (ii) LFs derived from IPF patients (IPF-LFs) with a high baseline of senescence; or (iii) senescence-induced A549 cells, an AEC line. Additionally, ratios of non-senescent Ctrl-LFs and senescence-induced Ctrl-LFs (100:0, 0:100, 50:50, 90:10, 99:1) were co-cultured and their effect on induction of senescence measured. We demonstrated that exposure of naïve non-senescent Ctrl-LFs to CM from senescence-induced Ctrl-LFs and AECs and IPF-LFs increased the markers of senescence including nuclear localisation of phosphorylated-H2A histone family member X (H2AXγ) and expression of p21, IL-6 and IL-8 in Ctrl-LFs. Additionally, co-cultures of non-senescent and senescence-induced Ctrl-LFs induced a senescent-like phenotype in the non-senescent cells. These data suggest that the phenomenon of “senescence-induced senescence” can occur in vitro in primary cultures of human LFs, and provides a possible explanation for the abnormal abundance of senescent cells in the lungs of IPF patients]]> Thu 27 Oct 2022 12:28:40 AEDT ]]> β-Adrenergic Receptor Stimulation Maintains NCX-CaMKII Axis and Prevents Overactivation of IL6R-Signaling in Cardiomyocytes upon Increased Workload https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52685 Fri 20 Oct 2023 10:05:02 AEDT ]]> Cannabis sativa: Interdisciplinary Strategies and Avenues for Medical and Commercial Progression Outside of CBD and THC https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49409 Fri 12 May 2023 14:55:34 AEST ]]> Selenium and arsenic levels, prevalence of common variants of genes involved in their metabolism, and psoriasis disease https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:55958 Fri 12 Jul 2024 10:32:02 AEST ]]> Low blood-as levels and selected genotypes appears to be promising biomarkers for occurrence of colorectal cancer in women https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49791 Fri 02 Jun 2023 17:14:07 AEST ]]>